Principally, the INSF antibody is being assessed for its ability to treat neuropathic pain. Additionally, it is also
being tested for therapeutic benefits in various animal models of motor neuron related and psychiatric disorders,
such as epilepsy, schizophrenia and autism as well.
- ① Neuropathic pain: Neuropathic pain is a symptom associated with peripheral nerve damage such as a traumatic injury, diabetes or infections. The physiological processes involved in moderating pain sensation can be quite complex. Unfortunately, subsequent to some injuries pain may persist even after the initial injury might have healed. Only 40-60% of patients gain partial relief by current medications, namely anti-convulsants and opioid analgesics.