• R&D
  • Technology

R&D

Technology

Neuracle Science Technology

NS350

Pipeline NS350
Summary NS350 is a small-molecule drug candidate designed to bind to FAM19A5, inhibiting its binding to LRRC4B. In collaboration with Arontier and the Korea University College of Pharmacy, we have identified the core structure of the FAM19A5 protein.
Based on the structure, we are developing small molecule compounds with high binding affinity to FAM19A5, low cytotoxicity, high solubility in solvents and pharmacologically stable structure. The discovered compounds will be developed into orally administered drugs.

AI-based prediction of the binding structure of FAM19A5 and LRRC4B, leading to small molecules predicted to bind to the site

Small Molecule Compound Discovery Using AI-Backed Structure Analysis

Discovery and validation of lead compound (NS350) through medicinal chemistry methods

Small Molecule Compound Disign Using AI-Backed Structure Analysis